YK340 Substance P (Saliva) EIA Kit
Introduction
Substance P is a peptide composed of a chain of 11 amino acid residues, which is one of a member of neuropeptides with similar structure called tachykinin.
Substance P was first found to function as a neurotransmitter, and subsequent research has shown that it is expressed not only in the central and peripheral nervous systems, but also in peripheral non-nervous cells, and is now involved in a wide range of physiological functions. It is also known to be associated with various pathologies.
Pneumonia is considered to be one of the major causes of death among the elderly in Japan, and decreased secretion of substance P leads to a decrease in normal swallowing reflex and cough reflex, which increases silent aspiration, it has been pointed out that the risk of aspiration pneumonia is increased as a result.
Saliva can be collected easily and noninvasively, and Substance P concentration in saliva is considered to be a useful biomarker.
▼This kit can specifically and easily measure Substance P present in saliva.
▼The assay kit can measure Substance P in saliva within the range of 6.859-5,000 pg/mL
▼The assay is completed within 18 hr.+1.5 hr.
▼Test sample: Human saliva
▼Sample volume: 50 μL
| <Crossreactivity> | |
| Related peptides | Crossreactivity（％） |
| Substance P (1-4) | < 0.1 |
| Substance P (3-11) amide | 86.5 |
| Substance P (4-11) amide | 99.1 |
| Substance P (7-11) amide | 48.8 |
| Neurokinin A | 0.3 |
| Neurokinin B | 0.1 |
| Hemokinin-1 (human) | 86.2 |