References for YK090 Glucagon EIA Kit

1.
Regulation of alpha-cell function by the beta-cell during hypoglycemia in Wistar rats: the "switch-off" hypothesis.
Zhou H, Tran PO, Yang S, Zhang T, LeRoy E, Oseid E, Robertson RP.
Diabetes. 2004 Jun;53(6):1482-7.
(Full)
2. Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue.
Maeda N, Funahashi T, Hibuse T, Nagasawa A, Kishida K, Kuriyama H, Nakamura T, Kihara S, Shimomura I, Matsuzawa Y.
Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17801-6. Epub 2004 Dec 10.
(Full)
3.
The ablation of the Ca(v)2.3/E-type voltage-gated Ca2+ channel causes a mild phenotype despite an altered glucose induced glucagon response in isolated islets of Langerhans.
Pereverzev A, Salehi A, Mikhna M, Renstrom E, Hescheler J, Weiergraber M, Smyth N, Schneider T.
Eur J Pharmacol. 2005 Mar 21;511(1):65-72.
(Abs)
4.
Protective effect of brain-derived neurotrophic factor on pancreatic islets in obese diabetic mice.
Yamanaka M, Itakura Y, Inoue T, Tsuchida A, Nakagawa T, Noguchi H, Taiji M.
Metabolism. 2006 Oct;55(10):1286-92.
(Abs)
5. Transforming growth factor-beta in the brain regulates fat metabolism during endurance exercise.
Ishikawa T, Mizunoya W, Shibakusa T, Inoue K, Fushiki T.
Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1151-9. Epub 2006 Jul 5.
(Full)
6.
Adult pancreatic islets require differential pax6 gene dosage.
Hamasaki A, Yamada Y, Kurose T, Ban N, Nagashima K, Takahashi A, Fujimoto S, Shimono D, Fujiwara M, Toyokuni S, Seino Y, Inagaki N.
Biochem Biophys Res Commun. 2007 Feb 2;353(1):40-6. Epub 2006 Dec 4.
(Abs)
7.
Hypoglycemic effect of isoleucine involves increased muscle glucose uptake and whole body glucose oxidation and decreased hepatic gluconeogenesis.
Doi M, Yamaoka I, Nakayama M, Sugahara K, Yoshizawa F.
Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1683-93. Epub 2007 Feb 13.
(Full)
8.
Comparison of the antidiabetic effects of brain-derived neurotrophic factor and thiazolidinediones in obese diabetic mice.
Yamanaka M, Itakura Y, Tsuchida A, Nakagawa T, Noguchi H, Taiji M.
Diabetes Obes Metab. 2007 Nov;9(6):879-88.
(Abs)
9.
Hypoglycemic effect of Chlorella vulgaris intake in type 2 diabetic Goto-Kakizaki and normal Wistar rats.
Jeong H, Kwon HJ, Kim MK.
Nutr Res Pract. 2009 Spring;3(1):23-30. Epub 2009 Mar 31.
(Full)
10.
Adiposity-related biochemical phenotype in senescence-accelerated mouse prone 6 (SAMP6).
Niimi K, Takahashi E, Itakura C.
Comp Med. 2009 Oct;59(5):431-6.
(Full)
11.
ƒΐ3-adrenoceptor-mediated increased circulating transaminase levels in mice treated with its agonist BRL 37344.
Kasahara H, Muto S, Motokawa Y, Arisaka N, Kobayashi S, Souma S, Kuroda J.
J Toxicol Sci. 2010;35(5):779-84.
(Full)
12.
Raldh3 expression in diabetic islets reciprocally regulates secretion of insulin and glucagon from pancreatic islets.
Shimamura M, Karasawa H, Sakakibara S, Shinagawa A.
Biochem Biophys Res Commun. 2010 Oct 8;401(1):79-84. Epub 2010 Sep 15.
(Abs)
13.
Bone marrow-derived mesenchymal stromal cells support rat pancreatic islet survival and insulin secretory function in vitro.
Jung EJ, Kim SC, Wee YM, Kim YH, Choi MY, Jeong SH, Lee J, Lim DG, Han DJ.
Cytotherapy. 2011 Jan;13(1):19-29.
(Abs)
14.
Inhalable sustained-release formulation of glucagon: in vitro amyloidogenic and inhalation properties, and in vivo absorption and bioactivity.
Onoue S, Kuriyama K, Uchida A, Mizumoto T, Yamada S.
Pharm Res. 2011 May;28(5):1157-66. Epub 2011 Feb 2.
(Abs)
15.
Liver autophagy contributes to the maintenance of blood glucose and amino acid levels.
Ezaki J, Matsumoto N, Takeda-Ezaki M, Komatsu M, Takahashi K, Hiraoka Y, Taka H, Fujimura T, Takehana K, Yoshida M, Iwata J, Tanida I, Furuya N, Zheng DM, Tada N, Tanaka K, Kominami E, Ueno T.
Autophagy. 2011 Jul;7(7):727-36. Epub 2011 Jul 1.
(Full)
16.
Reduction of both beta cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice.
Takeda Y, Fujita Y, Honjo J, Yanagimachi T, Sakagami H, Takiyama Y, Makino Y, Abiko A, Kieffer TJ, Haneda M.
Diabetologia. 2011 Nov 10. [Epub ahead of print]
(Full)
17.
Endoplasmic Reticulum Stress Inhibits STAT3-Dependent Suppression of Hepatic Gluconeogenesis via Dephosphorylation and Deacetylation.
Kimura K, Yamada T, Matsumoto M, Kido Y, Hosooka T, Asahara S, Matsuda T, Ota T, Watanabe H, Sai Y, Miyamoto K, Kaneko S, Kasuga M, Inoue H.
Diabetes. 2012 Jan;61(1):61-73. Epub 2011 Nov 28.
(Abs)
18.
Beneficial effects of exendin-4 on experimental polyneuropathy in diabetic mice.
Himeno T, Kamiya H, Naruse K, Harada N, Ozaki N, Seino Y, Shibata T, Kondo M, Kato J, Okawa T, Fukami A, Hamada Y, Inagaki N, Seino Y, Drucker DJ, Oiso Y, Nakamura J.
Diabetes. 2011 Sep;60(9):2397-406. Epub 2011 Aug 1.
(Full)
19.
Amylin improves the effect of leptin on insulin sensitivity in leptin-resistant diet-induced obese mice.
Kusakabe T, Ebihara K, Sakai T, Miyamoto L, Aotani D, Yamamoto Y, Yamamoto-Kataoka S, Aizawa-Abe M, Fujikura J, Hosoda K, Nakao K.
Am J Physiol Endocrinol Metab. 2012 Jan 24. [Epub ahead of print]
(Abs)
20.
Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic mice.
Naito M, Fujikura J, Ebihara K, Miyanaga F, Yokoi H, Kusakabe T, Yamamoto Y, Son C, Mukoyama M, Hosoda K, Nakao K.
Diabetes. 2011 Sep;60(9):2265-73. Epub 2011 Aug 1.
(Full)
21.

The Deleterious Effect of Bariatric Surgery on Cortical and Trabecular Bone Density in the Femurs of Non-obese, Type 2 Diabetic Goto-Kakizaki Rats.

Perez-Castrillon JL, Riancho JA, de Luis D, Caeiro JR, Guede D, Gonzalez-Sagrado M, Ruiz-Mambrilla M, Domingo-Andres M, Conde R, Primo-Martin D.

Obes Surg. 2012 Aug 22. [Epub ahead of print]
(Abs)

22.
Genistein reduced insulin resistance index through modulating lipid metabolism in ovariectomized rats.
Choi JS, Koh IU, Song J.
Nutr Res. 2012 Nov;32(11):844-55. doi: 10.1016/j.nutres.2012.10.002. Epub 2012 Nov 8.
(Abs)
23. Extracellular Signal-Regulated Kinase in the Ventromedial Hypothalamus Mediates Leptin-Induced Glucose Uptake in Red-Type Skeletal Muscle.
Toda C, Shiuchi T, Kageyama H, Okamoto S, Coutinho EA, Sato T, Okamatsu-Ogura Y, Yokota S, Takagi K, Tang L, Saito K, Shioda S, Minokoshi Y.
Diabetes. 2013 Mar 25. [Epub ahead of print]
24. The Novel Oral Drug Subetta Exerts an Antidiabetic Effect in the Diabetic Goto-Kakizaki Rat: Comparison with Rosiglitazone
Danielle Bailbe, Erwann Philippe, Evgeniy Gorbunov, Sergey Tarasov, Oleg Epstein, and Bernard Portha
Journal of Diabetes Research
Volume 2013 (2013), Article ID 763125, 9 pages (Full)
25. The Keap1-Nrf2 System Prevents Onset of Diabetes Mellitus.
Uruno A, Furusawa Y, Yagishita Y, Fukutomi T, Muramatsu H, Negishi T, Sugawara A, Kensler TW, Yamamoto M.

Source

Mol Cell Biol. 2013 May 28. [Epub ahead of print] (Abs)
26.

Conditional VHL Gene Deletion Causes Hypoglycemic Death Associated with Disproportionately Increased Glucose Uptake by Hepatocytes through an Upregulated IGF-I Receptor.

Kurabayashi A, Kakinuma Y, Morita T, Inoue K, Sato T, Furihata M.

PLoS One. 2013 Jul 9;8(7):e69139. doi: 10.1371/journal.pone.0069139. Print 2013.(Full)

27.

Elimination of von hippel-lindau function perturbs pancreas endocrine homeostasis in mice.

Puri S, Garcia-Nunez A, Hebrok M, Cano DA.

PLoS One. 2013 Aug 20;8(8):e72213. doi: 10.1371/journal.pone.0072213.(Full)

28. Circulating glucagon to ghrelin ratio as a determinant of insulin resistance in hyperthyroidism.
Agbaht K, Erdogan MF, Emral R, Baskal N, Gullu S.
Endocrine. 2014 Feb;45(1):106-13. doi: 10.1007/s12020-013-9951-9. Epub 2013 Apr 10.
(Abs)
29.

Nrf2 Protects Pancreatic ƒΐ-Cells from Oxidative and Nitrosative Stress in Diabetic Model Mice.
Yagishita Y, Fukutomi T, Sugawara A, Kawamura H, Takahashi T, Pi J, Uruno A, Yamamoto M.
Diabetes. 2013 Nov 1. [Epub ahead of print]
(Abs)

30.
Intestinal gluconeogenesis is crucial to maintain a physiological fasting glycemia in the absence of hepatic glucose production in mice.

Penhoat A, Fayard L, Stefanutti A, Mithieux G, Rajas F.
Metabolism. 2014 Jan;63(1):104-11. doi: 10.1016/j.metabol.2013.09.005. Epub 2013 Oct 14.(PDF)

31.

Protective effects of pioglitazone and/or liraglutide on pancreatic ƒΐ-cells in db/db mice:Comparison of their effects between in an early and advanced stage of diabetes.

Kimura T, Kaneto H, Shimoda M, Hirukawa H, Okauchi S, Kohara K, Hamamoto S, Tawaramoto K, Hashiramoto M, Kaku K.

Mol Cell Endocrinol. 2015 Jan 15;400:78-89. doi: 10.1016/j.mce.2014.11.018. Epub 2014 Nov 24.

PMID: 
25463759 
[PubMed - in process] 
Free Article
32. A treadmill exercise reactivates the signaling of the mammalian target of rapamycin (mTor) in the skeletalmuscles of starved mice.
Zheng DM, Bian Z, Furuya N, Oliva Trejo JA, Takeda-Ezaki M, Takahashi K, Hiraoka Y, Mineki R, Taka H, Ikeda S, Komatsu M, Fujimura T, Ueno T, Ezaki J.  Biochem Biophys Res Commun. 2015 Jan 2;456(1):519-26. doi: 10.1016/j.bbrc.2014.11.118. Epub 2014 Dec 6.
(Abs)
33.
(Abs)
34. Diethyldithiocarbamate-mediated zinc ion chelation reveals role of Cav2.3 channels in glucagon secretion.
Drobinskaya I, Neumaier F, Pereverzev A, Hescheler J, Schneider T.
Biochim Biophys Acta. 2015 May;1853(5):953-64. doi: 10.1016/j.bbamcr.2015.01.001. Epub 2015 Jan 17.
35. High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice (Full PDF)
Takanori Shinjo, Yusuke Nakatsu, Misaki Iwashita, Tomomi Sano, Hideyuki Sakoda, Hisamitsu Ishihara, Akifumi Kushiyama, Midori Fujishiro, Fusanori Nishimura and Tomoichiro Asano Diabetology & Metabolic Syndrome Sample doi:10.1186/s13098-015-0047-y
36.
Combination of DPP-4 inhibitor and PPARƒΑ agonist exerts protective effects on pancreatic ƒΐ-cells in diabeticdb/db mice through the augmentation of IRS-2 expression. 
Hirukawa H, Kaneto H, Shimoda M, Kimura T, Okauchi S, Obata A, Kohara K, Hamamoto S, Tawaramoto K, Hashiramoto M3, Kaku K.
Mol Cell Endocrinol. 2015 Jun 25. pii: S0303-7207(15)00320-2. doi: 10.1016/j.mce.2015.06.010. [Epub ahead of print]
37. Role of large MAF transcription factors in the mouse endocrine pancreas.
Abdellatif AM, Ogata K, Kudo T, Xiafukaiti G, Chang YH, Katoh MC, El-Morsy SE, Oishi H, Takahashi S. Exp Anim. 2015 Apr 27. [Epub ahead of print]
38.

Vildagliptin preserves the mass and function of pancreatic ƒΐ cells via the developmental regulation and suppression of oxidative andendoplasmic reticulum stress in a mouse model of diabetes.
Hamamoto S, Kanda Y, Shimoda M, Tatsumi F, Kohara K, Tawaramoto K, Hashiramoto M, Kaku K.
Diabetes Obes Metab. 2013 Feb;15(2):153-63. doi: 10.1111/dom.12005. Epub 2012 Sep 25.

39. MIN6 Is Not a Pure Beta Cell Line but a Mixed Cell Line with Other Pancreatic Endocrine Hormones.
Koji NAKASHIMA, Yukiko KANDA, Yasushi HIROKAWA, Fumiko KAWASAKI, Michihiro MATSUKI, Kohei KAKU. Endocrine Journal, Vol. 56 (2009) No. 1 P 45-53
40.
High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans instreptozotocin-induced diabetic mice.
Shinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Nishimura F, Asano T.
Diabetol Metab Syndr. 2015 Jun 2;7:50. doi: 10.1186/s13098-015-0047-y. eCollection 2015.
41. Protective effects of pioglitazone and/or liraglutide on pancreatic ƒΐ-cells in db/db mice: Comparison of their effects between in an early and advanced stage of diabetes
Tomohiko Kimura, Masashi Shimoda, Hidenori Hirukawa, Seizo Okauchi, Kenji Kohara,Sumiko Hamamoto, Kazuhito Tawaramoto, Mitsuru Hashiramoto, Kohei Kaku
Molecular and Cellular Endocrinology, Volume 400, 15 January 2015, Pages 78-89
42. Combination of DPP-4 inhibitor and PPARƒΑ agonist exerts protective effects on pancreatic ƒΐ-cells in diabeticdb/db mice through the augmentation of IRS-2 expression.
Hirukawa H, Kaneto H, Shimoda M, Kimura T, Okauchi S, Obata A, Kohara K, Hamamoto S, Tawaramoto K, Hashiramoto M, Kaku K.
Mol Cell Endocrinol. 2015 Sep 15;413:49-60. doi: 10.1016/j.mce.2015.06.010. Epub 2015 Jun 25.
43. Nardilysin Is Required for Maintaining Pancreatic ƒΐ-Cell Function.
Nishi K, Sato Y, Ohno M, Hiraoka Y, Saijo S, Sakamoto J, Chen PM, Morita Y, Matsuda S, Iwasaki K, Sugizaki K, Harada N, Mukumoto Y,Kiyonari H, Furuyama K, Kawaguchi Y, Uemoto S, Kita T, Inagaki N, Kimura T, Nishi E.
Diabetes. 2016 Oct;65(10):3015-27. doi: 10.2337/db16-0178. Epub 2016 Jul 6.
44.

Hepatic role in an early glucose-lowering effect by a novel dipeptidyl peptidase 4 inhibitor, evogliptin, in a rodent model of type 2 diabetes.

Kim TH, Kim MK, Cheong YH, Chae YN, Lee Y, Ka SO, Jung IH, Shin CY, Bae EJ, Son MH.

Eur J Pharmacol. 2016 Jan 15;771:65-76. doi: 10.1016/j.ejphar.2015.11.029.

45.

Porcine skin gelatin hydrolysate as a dipeptidyl peptidase IV inhibitor improves glycemic control in streptozotocin-induced diabetic rats
Shih-Li Huanga,Chuan-Chuan Hung,Chia-Ling Jao,Yu-Shan Tung,Kuo-Chiang Hsu.
Journal of Functional Foods. Volume 11, November 2014, Pages 235-242
(Full PDF)

46. Effects of oral administration of gelatin capsules on plasma insulin and glucagon levels in dogs
Hideaki Yokoyama, Taku Masuyama, Tomio Ishida, Yusuke Suzuki, Toshiyuki Shoda, Hideyuki Kuno, Shoichiro Sugai
Fundamental Toxicological Sciences (2017) p. 9-14
(Full PDF)
47.
Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.
Hamada S, Shimosegawa T, Taguchi K, Nabeshima T, Yamamoto M, Masamune A.
Am J Physiol Gastrointest Liver Physiol. 2018 Jan 1;314(1):G65-G74. doi: 10.1152/ajpgi.00228.2017. Epub 2017 Sep 28.

(Abs)